You can now add levels of multires as simple subdivides instead of Catmull-Clark subdivides.  This is especially useful if you want the lower level to keep its position when adding new levels of multires.

Note however, that changes to multires at higher levels are still propogated to lower levels using the Catmull-Clark algorithm.

There is a new brush type 'Flatten'.  This brush pushes vertices along the normal defined by the average normal of each vertex within the brush area. The vertices are pushed towards the plane defined by vertices towards the edge of the brush. Essentially, this means that the direction of flattening is dependent on the surface beneath the brush.

A scaling factor has been added to sculpt brushes - this will make working on models that are extremely large or small scale much easier.