Blender is Customizable

Novice and advanced users will love the ability to customize their layout completely. From simply splitting their viewport, to fully customizing it with python scripting, Blender works for you.

Blender’s interface also offers:

Unlike Blender 2.7 (where most keys were already assigned), Blender 2.8 comes with a minimal keymap, giving you more room to assign new shortcuts to speed-up your workflow.

Custom preferences can be set per keymap for special actions such as selecting with left or right click, which action to perform with Spacebar, pie menus, and more.

Introduced in Blender 2.80, the built-in Industry Compatible will make it easier than ever for you to jump between applications.

Simply select it from the splash screen the first time you start Blender, or from the Preferences > Keymap section.